| Ident. | Authors (with country if any) | Title |
|---|
| 000991 (2020) |
Abdo A. Elfiky | Anti-HCV, nucleotide inhibitors, repurposing against COVID-19 |
| 000B45 (2019) |
Kouji Ohnishi [Japon] ; Yasunao Hattori [Japon] ; Kazuya Kobayashi [Japon] ; Kenichi Akaji [Japon] | Evaluation of a non-prime site substituent and warheads combined with a decahydroisoquinolin scaffold as a SARS 3CL protease inhibitor. |
| 000D69 (2017) |
Manfeng Zhang [République populaire de Chine] ; Xiaorong Li [République populaire de Chine] ; Zengqin Deng [République populaire de Chine] ; Zhenhang Chen [République populaire de Chine] ; Yang Liu [République populaire de Chine] ; Yina Gao [République populaire de Chine] ; Wei Wu [République populaire de Chine] ; Zhongzhou Chen [République populaire de Chine] | Structural Biology of the Arterivirus nsp11 Endoribonucleases. |
| 000E03 (2017) |
Jaimee R. Compton [États-Unis] ; Matthew J. Mickey [États-Unis] ; Xin Hu [États-Unis] ; Juan J. Marugan [États-Unis] ; Patricia M. Legler [États-Unis] | Mutation of Asn-475 in the Venezuelan Equine Encephalitis Virus nsP2 Cysteine Protease Leads to a Self-Inhibited State. |
| 000E04 (2017) |
Manal Alfuwaires ; Abdallah Altaher ; Mahmoud Kandeel | Molecular Dynamic Studies of Interferon and Innate Immunity Resistance in MERS CoV Non-Structural Protein 3. |
| 000E12 (2017) |
Stephen A. Goldstein [États-Unis] ; Joshua M. Thornbrough [États-Unis] ; Rong Zhang [États-Unis] ; Babal K. Jha [États-Unis] ; Yize Li [États-Unis] ; Ruth Elliott [États-Unis] ; Katherine Quiroz-Figueroa [États-Unis] ; Annie I. Chen [États-Unis] ; Robert H. Silverman [États-Unis] ; Susan R. Weiss [États-Unis] | Lineage A Betacoronavirus NS2 Proteins and the Homologous Torovirus Berne pp1a Carboxy-Terminal Domain Are Phosphodiesterases That Antagonize Activation of RNase L. |
| 000F11 (2016) |
Sarah E. St. John ; Brandon J. Anson ; Andrew D. Mesecar | X-Ray Structure and Inhibition of 3C-like Protease from Porcine Epidemic Diarrhea Virus |
| 000F39 (2016) |
Gang Ye [République populaire de Chine] ; Feng Deng [République populaire de Chine] ; Zhou Shen [République populaire de Chine] ; Rui Luo [République populaire de Chine] ; Ling Zhao [République populaire de Chine] ; Shaobo Xiao [République populaire de Chine] ; Zhen F. Fu [République populaire de Chine, États-Unis] ; Guiqing Peng [République populaire de Chine] | Structural basis for the dimerization and substrate recognition specificity of porcine epidemic diarrhea virus 3C-like protease |
| 000F99 (2016) |
Xin Hu [États-Unis] ; Jaimee R. Compton [États-Unis] ; Dagmar H. Leary [États-Unis] ; Mark A. Olson [États-Unis] ; Michael S. Lee [États-Unis] ; Jonah Cheung [États-Unis] ; Wenjuan Ye [États-Unis] ; Mark Ferrer [États-Unis] ; Noel Southall [États-Unis] ; Ajit Jadhav [États-Unis] ; Elaine M. Morazzani [États-Unis] ; Pamela J. Glass [États-Unis] ; Juan Marugan [États-Unis] ; Patricia M. Legler [États-Unis] | Kinetic, Mutational, and Structural Studies of the Venezuelan Equine Encephalitis Virus Nonstructural Protein 2 Cysteine Protease. |
| 001063 (2016) |
Chunmei Li [République populaire de Chine] ; Xin Teng [République populaire de Chine] ; Yifei Qi [République populaire de Chine] ; Bo Tang [République populaire de Chine] ; Hailing Shi [République populaire de Chine] ; Xiaomin Ma [République populaire de Chine] ; Luhua Lai [République populaire de Chine] | Conformational Flexibility of a Short Loop near the Active Site of the SARS-3CLpro is Essential to Maintain Catalytic Activity. |
| 001206 (2015) |
Arthur Weininger [Canada] ; Susan Weininger [Canada] | Using common spatial distributions of atoms to relate functionally divergent influenza virus N10 and N11 protein structures to functionally characterized neuraminidase structures, toxin cell entry domains, and non-influenza virus cell entry domains. |
| 001237 (2015) |
Danielle Needle [États-Unis] ; George T. Lountos [États-Unis] ; David S. Waugh [États-Unis] | Structures of the Middle East respiratory syndrome coronavirus 3C-like protease reveal insights into substrate specificity. |
| 001297 (2015) |
Hyun Lee [États-Unis] ; Hao Lei [États-Unis] ; Bernard D. Santarsiero [États-Unis] ; Joseph L. Gatuz [États-Unis] ; Shuyi Cao [États-Unis] ; Amy J. Rice [États-Unis] ; Kavankumar Patel [États-Unis] ; Michael Z. Szypulinski [États-Unis] ; Isabel Ojeda ; Arun K. Ghosh [États-Unis] ; Michael E. Johnson [États-Unis] | Inhibitor recognition specificity of MERS-CoV papain-like protease may differ from that of SARS-CoV. |
| 001307 (2015) |
Michael Berry [Afrique du Sud] ; Burtram Fielding [Afrique du Sud] ; Junaid Gamieldien [Afrique du Sud] | Human coronavirus OC43 3CL protease and the potential of ML188 as a broad-spectrum lead compound: homology modelling and molecular dynamic studies. |
| 001335 (2015) |
Sheng Liu [République populaire de Chine] ; Wanxing Wei [République populaire de Chine] ; Yubin Li [République populaire de Chine] ; Xu Liu [République populaire de Chine] ; Xiaoji Cao [République populaire de Chine] ; Kechan Lei [République populaire de Chine] ; Min Zhou [République populaire de Chine] | Design, synthesis, biological evaluation and molecular docking studies of phenylpropanoid derivatives as potent anti-hepatitis B virus agents. |
| 001412 (2015) |
Jingjing Gao [République populaire de Chine] ; Xianjin Luo [République populaire de Chine] ; Yuhuan Li [République populaire de Chine] ; Rongmei Gao [République populaire de Chine] ; Haifeng Chen [République populaire de Chine] ; Dingjue Ji [République populaire de Chine] | Synthesis and Biological Evaluation of 2‐oxo‐pyrazine‐3‐carboxamide‐yl Nucleoside Analogues and Their Epimers as Inhibitors of Influenza A Viruses |
| 001569 (2014) |
Kiira Ratia [États-Unis] ; Andrew Kilianski [États-Unis] ; Yahira M. Baez-Santos [États-Unis] ; Susan C. Baker [États-Unis] ; Andrew Mesecar [États-Unis] | Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating activity of SARS-CoV papain-like protease. |
| 001591 (2014) |
Xingxing Yang [République populaire de Chine] ; Xiaojuan Chen [République populaire de Chine] ; Guangxing Bian [République populaire de Chine] ; Jian Tu [Australie] ; Yaling Xing [République populaire de Chine] ; Yayun Wang [République populaire de Chine] ; Zhongbin Chen [République populaire de Chine] | Proteolytic processing, deubiquitinase and interferon antagonist activities of Middle East respiratory syndrome coronavirus papain-like protease. |
| 001667 (2014) |
Zhaoqiang Liu [République populaire de Chine] ; Wenmin Chen [République populaire de Chine] ; Peng Zhan [République populaire de Chine] ; Erik De Clercq [Belgique] ; Christophe Pannecouque [Belgique] ; Xinyong Liu [République populaire de Chine] | Design, synthesis and anti-HIV evaluation of novel diarylnicotinamide derivatives (DANAs) targeting the entrance channel of the NNRTI binding pocket through structure-guided molecular hybridization. |
| 001670 (2014) |
Jian Lei [Allemagne] ; Jeroen R. Mesters [Allemagne] ; Christian Drosten [Allemagne] ; Stefan Anemüller [Allemagne] ; Qingjun Ma [Allemagne] ; Rolf Hilgenfeld [Allemagne] | Crystal structure of the papain-like protease of MERS coronavirus reveals unusual, potentially druggable active-site features. |
| 001920 (2013) |
Daniela Meyer [Allemagne] ; Frank Sielaff ; Maya Hammami ; Eva Böttcher-Friebertsh User ; Wolfgang Garten ; Torsten Steinmetzer | Identification of the first synthetic inhibitors of the type II transmembrane serine protease TMPRSS2 suitable for inhibition of influenza virus activation. |
| 002114 (2011) |
Tohru Miyoshi-Akiyama [Japon] ; Isao Ishida ; Masaya Fukushi ; Keina Yamaguchi ; Yusuke Matsuoka ; Takashi Ishihara ; Masayoshi Tsukahara ; Seisuke Hatakeyama ; Norikazu Itoh ; Aki Morisawa ; Yoshiyuki Yoshinaka ; Naoki Yamamoto ; Zhang Lianfeng ; Qin Chuan ; Teruo Kirikae ; Takehiko Sasazuki | Fully human monoclonal antibody directed to proteolytic cleavage site in severe acute respiratory syndrome (SARS) coronavirus S protein neutralizes the virus in a rhesus macaque SARS model. |
| 002437 (2010) |
R. Ramajayam [Taïwan] ; Kian-Pin Tan ; Hun-Ge Liu ; Po-Huang Liang | Synthesis and evaluation of pyrazolone compounds as SARS-coronavirus 3C-like protease inhibitors. |
| 002438 (2010) |
Xianfeng Li [États-Unis] ; Yong-Kang Zhang ; Yang Liu ; Charles Z. Ding ; Qun Li ; Yasheen Zhou ; Jacob J. Plattner ; Stephen J. Baker ; Xuelei Qian ; Dazhong Fan ; Liang Liao ; Zhi-Jie Ni ; Gemma V. White ; Jackie E. Mordaunt ; Linos X. Lazarides ; Martin J. Slater ; Richard L. Jarvest ; Pia Thommes ; Malcolm Ellis ; Colin M. Edge ; Julia A. Hubbard ; Don Somers ; Paul Rowland ; Pamela Nassau ; Bill Mcdowell ; Tadeusz J. Skarzynski ; Wieslaw M. Kazmierski ; Richard M. Grimes ; Lois L. Wright ; Gary K. Smith ; Wuxin Zou ; Jon Wright ; Lewis E. Pennicott | Synthesis and evaluation of novel alpha-amino cyclic boronates as inhibitors of HCV NS3 protease. |
| 002577 (2010) |
Young Bae Ryu [Corée du Sud] ; Hyung Jae Jeong ; Jang Hoon Kim ; Young Min Kim ; Ji-Young Park ; Doman Kim ; Thi Thanh Hanh Nguyen ; Su-Jin Park ; Jong Sun Chang ; Ki Hun Park ; Mun-Chual Rho ; Woo Song Lee | Biflavonoids from Torreya nucifera displaying SARS-CoV 3CL(pro) inhibition. |
| 002B97 (2009) |
Krongsakda Phakthanakanok [Thaïlande] ; Khanok Ratanakhanokchai ; Khin Lay Kyu ; Pornthep Sompornpisut ; Aaron Watts ; Surapong Pinitglang | A computational analysis of SARS cysteine proteinase-octapeptide substrate interaction: implication for structure and active site binding mechanism. |
| 003049 (2008) |
Alex G. Taranto [Brésil] ; Paulo Carvalho ; Mitchell A. Avery | QM/QM studies for Michael reaction in coronavirus main protease (3CL Pro). |
| 003057 (2008) |
Marcin Drag [États-Unis] ; Jowita Mikolajczyk ; Miklos Bekes ; Francisca E. Reyes-Turcu ; Jonathan A. Ellman ; Keith D. Wilkinson ; Guy S. Salvesen | Positional-scanning fluorigenic substrate libraries reveal unexpected specificity determinants of DUBs (deubiquitinating enzymes). |
| 003584 (2007) |
D H Goetz [États-Unis] ; Y. Choe ; E. Hansell ; Y T Chen ; M. Mcdowell ; C B Jonsson ; W R Roush ; J. Mckerrow ; C S Craik | Substrate specificity profiling and identification of a new class of inhibitor for the major protease of the SARS coronavirus. |
| 003613 (2007) |
Hui-Ping Chang ; Chi-Yuan Chou ; Gu-Gang Chang | Reversible Unfolding of the Severe Acute Respiratory Syndrome Coronavirus Main Protease in Guanidinium Chloride |
| 003671 (2007) |
Kewen Zheng [République populaire de Chine] ; Guozheng Ma ; Jinming Zhou ; Min Zen ; Wenna Zhao ; Yongjun Jiang ; Qingsen Yu ; Jialiang Feng | Insight into the activity of SARS main protease: Molecular dynamics study of dimeric and monomeric form of enzyme. |
| 003C69 (2006) |
Jiahai Shi [Singapour] ; Jianxing Song | The catalysis of the SARS 3C-like protease is under extensive regulation by its extra domain. |
| 003C91 (2006) |
Rolf Hilgenfeld [Allemagne] ; Kanchan Anand ; Jeroen R. Mesters ; Zihe Rao ; Xu Shen ; Hualiang Jiang ; Jinzhi Tan ; Koen H G. Verschueren | Structure and dynamics of SARS coronavirus main proteinase (Mpro). |
| 003D57 (2006) |
Luhua Lai [République populaire de Chine] ; Xiaofeng Han ; Hao Chen ; Ping Wei ; Changkang Huang ; Shiyong Liu ; Keqiang Fan ; Lu Zhou ; Zhenming Liu ; Jianfeng Pei ; Ying Liu | Quaternary structure, substrate selectivity and inhibitor design for SARS 3C-like proteinase. |
| 003F15 (2006) |
Haitao Yang [République populaire de Chine] ; Mark Bartlam ; Zihe Rao | Drug design targeting the main protease, the Achilles' heel of coronaviruses. |
| 003F26 (2006) |
Naina Barretto [États-Unis] ; Dalia Jukneliene ; Kiira Ratia ; Zhongbin Chen ; Andrew D. Mesecar ; Susan C. Baker | Deubiquitinating activity of the SARS-CoV papain-like protease. |
| 003F35 (2006) |
Stefano Ricagno ; Marie-Pierre Egloff ; Rachel Ulferts [Royaume-Uni] ; Bruno Coutard ; Didier Nurizzo [France] ; Valérie Campanacci [France] ; Christian Cambillau [France] ; John Ziebuhr [Royaume-Uni] ; Bruno Canard | Crystal structure and mechanistic determinants of SARS coronavirus nonstructural protein 15 define an endoribonuclease family |
| 004139 (2006) |
Marcin Hoffmann [Pologne] ; Krystian Eitner [Pologne] ; Marcin Von Grotthuss [Pologne] ; Leszek Rychlewski [Pologne] ; Ewa Banachowicz [Pologne] ; Tomasz Grabarkiewicz [Pologne] ; Tomasz Szkoda [Pologne] ; Andrzej Kolinski [Pologne] | Three dimensional model of severe acute respiratory syndrome coronavirus helicase ATPase catalytic domain and molecular design of severe acute respiratory syndrome coronavirus helicase inhibitors |
| 004380 (2006) |
Isabelle Imbert [France] ; Jean-Claude Guillemot [France] ; Jean-Marie Bourhis [France] ; Cécile Bussetta [France] ; Bruno Coutard [France] ; Marie-Pierre Egloff [France] ; François Ferron [France] ; Alexander E. Gorbalenya [Pays-Bas] ; Bruno Canard [France] | A second, non‐canonical RNA‐dependent RNA polymerase in SARS Coronavirus |
| 004611 (2005) |
Ting Xu [Singapour] ; Amy Ooi ; Hooi Chen Lee ; Rupert Wilmouth ; Ding Xiang Liu ; Julien Lescar | Structure of the SARS coronavirus main proteinase as an active C2 crystallographic dimer. |
| 004832 (2005) |
Ao Cheng [République populaire de Chine] ; Wei Zhang ; Youhua Xie ; Weihong Jiang ; Eddy Arnold ; Stefan G. Sarafianos ; Jianping Ding | Expression, purification, and characterization of SARS coronavirus RNA polymerase. |
| 004973 (2005) |
Yu-San Han [République populaire de Chine] ; Gu-Gang Chang [République populaire de Chine] ; Chiun-Gung Juo [République populaire de Chine] ; Hong-Jen Lee [République populaire de Chine] ; Shiou-Hwei Yeh [République populaire de Chine] ; John Tsu-An Hsu [République populaire de Chine] ; Xin Chen [République populaire de Chine, Taïwan] | Papain-Like Protease 2 (PLP2) from Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV): Expression, Purification, Characterization, and Inhibition† |
| 004B13 (2005) |
Wenhui Li [États-Unis] ; Chengsheng Zhang [Canada, République populaire de Chine] ; Jianhua Sui [États-Unis] ; Jens H. Kuhn [États-Unis, Allemagne] ; Michael J. Moore [États-Unis] ; Shiwen Luo [République populaire de Chine] ; Swee-Kee Wong [États-Unis] ; I-Chueh Huang [États-Unis] ; Keming Xu [République populaire de Chine] ; Natalya Vasilieva [États-Unis] ; Akikazu Murakami [États-Unis] ; Yaqing He [République populaire de Chine] ; Wayne A. Marasco [États-Unis] ; Yi Guan [République populaire de Chine, Hong Kong] ; Hyeryun Choe [États-Unis, Hong Kong] ; Michael Farzan [États-Unis, Hong Kong] | Receptor and viral determinants of SARS‐coronavirus adaptation to human ACE2 |
| 005315 (2004) |
Arezki Azzi [Canada] ; Sheng-Xiang Lin | Human SARS-coronavirus RNA-dependent RNA polymerase: activity determinants and nucleoside analogue inhibitors. |
| 005562 (2004) |
Usman Bacha [États-Unis] ; Jennifer Barrila [États-Unis] ; Adrian Velazquez-Campoy [États-Unis] ; Stephanie A. Leavitt [États-Unis] ; Ernesto Freire [États-Unis] | Identification of Novel Inhibitors of the SARS Coronavirus Main Protease 3CLpro† |
| 005E95 (2003) |
Xiao-Jing Yu [République populaire de Chine] ; Cheng Luo ; Jian-Cheng Lin ; Pei Hao ; You-Yu He ; Zong-Ming Guo ; Lei Qin ; Jiong Su ; Bo-Shu Liu ; Yin Huang ; Peng Nan ; Chuan-Song Li ; Bin Xiong ; Xiao-Min Luo ; Guo-Ping Zhao ; Gang Pei ; Kai-Xian Chen ; Xu Shen ; Jian-Hua Shen ; Jian-Ping Zou ; Wei-Zhong He ; Tie-Liu Shi ; Yang Zhong ; Hua-Liang Jiang ; Yi-Xue Li | Putative hAPN receptor binding sites in SARS_CoV spike protein. |
| 005F28 (2003) |
Xiang Xu [République populaire de Chine] ; Yunqing Liu ; Susan Weiss ; Eddy Arnold ; Stefan G. Sarafianos ; Jianping Ding | Molecular model of SARS coronavirus polymerase: implications for biochemical functions and drug design. |
| 005F35 (2003) |
Volker Thiel [Allemagne] ; Konstantin A. Ivanov [Allemagne] ; Ákos Putics [Allemagne] ; Tobias Hertzig [Allemagne] ; Barbara Schelle [Allemagne] ; Sonja Bayer [Allemagne] ; Benedikt Wei Brich [Allemagne] ; Eric J. Snijder [Pays-Bas] ; Holger Rabenau [Allemagne] ; Hans Wilhelm Doerr [Allemagne] ; Alexander E. Gorbalenya [Pays-Bas] ; John Ziebuhr [Allemagne] | Mechanisms and enzymes involved in SARS coronavirus genome expression. |
| 006039 (2003) |
Kanchan Anand [Allemagne] ; John Ziebuhr ; Parvesh Wadhwani ; Jeroen R. Mesters ; Rolf Hilgenfeld | Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs. |
